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<p><font face="Verdana, Arial, Helvetica, sans-serif" size="2"><b><font color="#000066">Proxeed
user survey results from the USA...?</font></b></font></p>
<p><font face="Verdana, Arial, Helvetica, sans-serif" size="2"><font face="Verdana, Arial, Helvetica, sans-serif" size="2" color="#000066">Proxeed™is
the only dietary supplement created specifically to support sperm
development and function. The most significant factor in male reproductive
health is sperm quality. When motility, rapid linear progression,
count, concentration and morphology are good, the couple’s chances
of conception improve. </font></font></p>
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<td><font face="Verdana, Arial, Helvetica, sans-serif" size="2"><b><font color="#000066"><img src="pics/proxeedmansm.jpg" width="85" height="182" align="right"></font></b></font></td>
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<li><font face="Verdana, Arial, Helvetica, sans-serif" size="2" color="#000066">38%
of men attempting pregnancy for the first time will have sperm quality
values associated with lower pregnancy rates. Ref 1. </font></li>
<li><font face="Verdana, Arial, Helvetica, sans-serif" size="2" color="#000066">Lower
pregnancy rates have even been observed in men with twice the sperm
count of World Health Organization’s lower standard limit. .Ref 2 </font></li>
</ul>
<p><font face="Verdana, Arial, Helvetica, sans-serif" size="2" color="#000066">Of
the 5,154 Proxeed™ users contacted in the USA, here’s what 1,182 responding
couples said about Proxeed™ in a recent user survey*… </font></p>
<ul>
<li><font face="Verdana, Arial, Helvetica, sans-serif" size="2" color="#000066">Nearly
one-third (31%) of the users reported pregnancy since taking Proxeed™.
</font></li>
<li><font face="Verdana, Arial, Helvetica, sans-serif" size="2" color="#000066">62%
of pregnancies occurred during the first 6 months of Proxeed™ use.</font></li>
<li><font face="Verdana, Arial, Helvetica, sans-serif" size="2" color="#000066">65%
of couples surveyed had been trying to conceive for more than 1 year
with 33% trying for more than 2 years. </font></li>
<li><font face="Verdana, Arial, Helvetica, sans-serif" size="2" color="#000066">More
than half (55%) of those recalling the results of their pre- and post-
semen analyses reported that their results improved after taking Proxeed™.</font></li>
<li><font face="Verdana, Arial, Helvetica, sans-serif" size="2" color="#000066">Pregnancy
rate was 28% among couples using Proxeed™ alone, with the adjunctive
use of ART the pregnancy rate improved to 36%. </font></li>
<li><font face="Verdana, Arial, Helvetica, sans-serif" size="2" color="#000066">In
a follow-up survey among couples with no ART use**, the pregnancy rate
was 55%. This result was the same in couples with or without a history
of varicocele.</font> </li>
</ul>
<p><font face="Verdana, Arial, Helvetica, sans-serif" size="2" color="#000066">References:
</font></p>
<p><font face="Verdana, Arial, Helvetica, sans-serif" size="2" color="#000066">1.
Bonde JPE, Ernst E, Jensen TK, Hjollund NHI, Kolstad H, Henriksen TB,
Scheike T, Giwercman A, Olsen J, Skakkabaek NE. Relation between semen
quality and fertility: a population-based study of 430 first-pregnancy
planners. Lancet 1998;352:1172-7. </font></p>
<p><font face="Verdana, Arial, Helvetica, sans-serif" size="2" color="#000066">2.
Zinaman MJ, Brown CC, Selevan SG, Clegg ED. Semen quality and human fertility:
a prospective study with healthy couples. J Androl 2000;21:145-53. </font></p>
<p><font face="Verdana, Arial, Helvetica, sans-serif" size="2" color="#000066">*
The Proxeed™ user survey was conducted in March, 2001, by Wirthlin Worldwide
on behalf of Sigma-Tau HealthScience, Inc. A total of 5,154 Proxeed™ users
received the self-reported survey and the response rate was 23%. A sample
size of 1,182 has a margin of error of +/ - 2.9% at the 95% confidence
level. </font></p>
<p><font face="Verdana, Arial, Helvetica, sans-serif" size="2" color="#000066">**
To evaluate the value of Proxeed™ supplementation in varicocele repair,
206 original respondents without ART involvement were re polled. </font></p>
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